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Current Aphasia Trials

CACTUS

University of Sheffield Study to assess the clinical and cost effectiveness of aphasia computer treatment CACTUS  (Rebecca Palmer)
Crosson B, Fabrizio KS, Singletary F, Cato MA, Wierenga CE, Parkinson RB, et al. Treatment of naming in nonfluent aphasia through manipulation of intention and attention: a phase 1 comparison of two novel treatments. Journal of the International Neuropsychological Society 2007;13:582-94.
* Crosson B. Treating intention in aphasia: neuroplastic substrates. ClinicalTrials.gov NCT00567242 2007.

FUATAC  

Küst J, Kuhn D, Wadehn J, Karbe H. Kommunikationsorientierte forced-use Therapie bei Aphasikern. http://www.refonet.de/veranstaltungen/documents/05004Posterrefonetupdate2007.pdf (last accessed 25 March 2012).
* Küst J. Forced Use Aphasia Therapy in the ACute phase (FUATAC). ISRCTN Register ISRCTN26390986 2007.

IHCOP

 
Woolf C. The effects of phoneme discrimination and semantic therapies for speech perception deficits in aphasia. National Research Register.
IMITATE  
* Lee J, Fowler R, Rodney D, Cherney L, Small SL. IMITATE: An intensive computer-based treatment for aphasia based on action observation and imitation. Aphasiology 2010;24(4):449-65.
Small S. Speech and language therapy after stroke. ClinicalTrials.gov NCT00713050 2010.
Kukkonen 2007  
Kukkonen T, Korpijaakko-Huuhka AM. How much is enough and when is the right time? What do we know about the good practice and timing of aphasia rehabilitation? In: British Aphasiology Society Biennial Conference. September 10-12 2007, Edinburgh, UK.
* Kukkonen T, Molnár G, Korpijaakko-Huuhka A-M. How much is enough and when is the right time? Developing strategies for assessing aphasia rehabilitation. In: 27th World Congress of the International Association of Logopedics and Phoniatrics, Copenhagen, Denmark. August 5-9 2007.
Maher 2008  
* Mayer L, DeBakey ME. An investigation of constraint induced language therapy for aphasia. NCT00223847.
Wu S. An investigation of constraint induced language therapy for treatment of aphasia. www.rorc.research.va.gov/Project_Template.cfm?Project_ID=2141693285 (accessed 25 March 2012).

 

MIT USA

 
Schlaug G, Marchina S, Norton A. From singing to speaking: why singing may lead to recovery of expressive language function in patients with Broca's aphasia. Music Perception 2008;25(4):315-23.
Schlaug G, Norton A, Marchina S, Zipse L, Wan CY. From singing to speaking: facilitating recovery from nonfluent aphasia. Future Neurology 2010;5(5):657-65.
Schlaug G, Norton A. Behavioral and neural correlates of melodic intonation therapy versus speech repetition therapy in patients with non-fluent aphasia. In: Proceedings of the International Stroke Conference 2009. February 18-20 2009. San Diego, CA. 2009 (Abst. CT P37).
* Schlaug G. Melodic Intonation Therapy (MIT). Stroke Trials Registry, Internet Stroke Center: www.strokecenter.org/trials/ 2009.
Schlaug G. Singing to speaking: observations in healthy singers and patients with Broca's aphasia. In:  , editor(s). American Association for the Advancement of Science Annual Meeting, 18-22nd February 2010, San Diego. http://aaas.confex.com/aaas/2010/webprogram/Paper1481.html. (last accessed 25 March 2012).

RATS-3  
http://www.eso-stroke.org/pdf/dtd2009/Rotterdam%20University%20Hospital.pdf (accessed 25 March 2012).

Raymer

 
Raymer AM. Treatment for word retrieval impairments in aphasia. ClinicalTrials.gov 2008.
SP-I-RiT  
Lauterbach M, Leal G, Aguiar M, Fonseca I, Farrajota L, Fonseca J, et al. Intensive vs conventional speech therapy in aphasia due to ischaemic stroke: a randomized controlled trial. In: Proceedings of the British Aphasiology Society 2007 Biennial Conference, Edinburgh, UK. 10-12 September 2007:67-8.